Faculty

Deborah K. McMahon, MD Associate Professor, Department of Medicine - School of Medicine (Primary Appointment), Department of Infectious Diseases and Microbiology - Graduate School of Public Health (Secondary Appointment) Medical Director of the Pitt Treatment Evaluation Unit, University of Pittsburgh Medical Center E-mail: mcmahon@msx.dept-med.pitt.edu Phone: 412-647-6710 Fax: 412-647-5519 Address: 3601 Fifth Avenue 614 Falk Medical Building Pittsburgh, PA 15213

Education

MD; Temple University; 1981

Research Interests

Treatment of HIV/AIDS, HIV clinical trials

Recent Publications

• Rinaldo, C.R., Huang, X-L., Fan, Z., Margolick, J.B., Borowski, L., Hoji, A., Kalinyak, C., McMahon, D.K., Riddler, S.A., Hildebrand, W.H., Day, R.B., and Mellors, J.W. (2000). Anti-human immunodeficiency virus type 1 (HIV-1) CD8+ T-lymphocyte reactivity during combination antiretroviral therapy in HIV-1 infected patients with advanced immunodeficiency. J. Virol. 5:4127-4138.
• Gulick, R.M., Mellors, J.W., Havlir, D., Eron, J.J., Meibohm, A., Condra, J.H., Valentine, F.T., McMahon, D., Gonzales, C., Jonas, L., Emini, E.A., Chodakewitz, J.A., Isaacs, R., and Richman, D.D. (2000). 3-year suppression of HIV viremia with indinavir, zidovudine, and lamivudine. Ann. Intern. Med. 133:35-39.
• Kalish, L.A., Collier, A.C., Flanigan, T.P., Kumar, P.V., and the Viral Activation Transfusion Study Group (VATS) (McMahon DK is a member of the VATS). (2000). Plasma human immunodeficiency virus type 1 (HIV-1) RNA load in men and women with advanced HIV-1 disease. J. Infect. Dis. 182:603-606.
• Collier, A.C., Kalish, L.A., Busch, M.P., Gernsheimer, T., Assmann, S.F., Lane, T.A., Asmuth, D.M., Lederman, M.M., Murphy, E.L., Kumar, P., Kelley, M., Flanigan, T.P., McMahon, D.K., Sacks, H.S., Kennedy, M.S., Holland, P.V. for the Viral Activation Transfusion Study Group. (2001). Leukocyte-reduced red blood cell transfusions in patients with anemia and human immunodeficiency virus infection. JAMA  285:1592-1601.
• McMahon, D.K., Lederman, M., Haas, D.W., Haubrich, R., Stanford, J., Cooney, E., Horton, J., Kelleher, D., Ross, L., Cutrell, A., Lee, D., Spreen, W., and Mellors, J.W.  (2001). Antiretroviral activity and safety of abacavir in combination with selected HIV-1 protease inhibitors in therapy naïve HIV-1 infected adults. Antiretroviral Therapy  6:105-114.
• Harrold, S.M., Wang, G., McMahon, D.K., Riddler, S.A., Mellors, J.W., Becker, J.T., Caldararo, R., Reinhart, T.A., Achim, C.L., and Wiley, C.A. (2002). Recovery of replication-competent HIV-1 infected circulating monocytes from individuals receiving antiretroviral therapy. AIDS Res. Hum. Retroviruses  18:6:00-00.
• Wu, H., Mellors, J., Ruan, P., McMahon D, Kelleher D, Lederman MM. Viral Dynamics and Their Relations to Baseline Factors and Longer-Term Virologic Responses in Treatment-Naive HIV-1 Infected Patients Receiving Abacavir in Combination with HIV-1 Protease Inhibitors, JAIDS 2003: 32, 557-564.
• Hirsch, M.S., Steigbigel, R.T., Staszewski, S., McMahon, D., Fischl, M.A., Hirschel, B., Squires, K., DiNubile, M.J., Harvey, C.M., Chen, J., Leavitt, R.Y. for the Protocol 039 Study Group. (2003). Long-term efficacy, safety, and tolerability of indinavir-based therapy in protease inhibitor-naïve adults with advanced HIV infection. CID  37:113-128.
• Gulick, R.M., Meibohm, A., Havlir, D.,. Eron, J.J., Mosley, A., Chodakewitz, J.A., Isaacs, R., Gonzalez, C., McMahon, D., Richman, D.D., Robertson, M. and Mellors, J.W.   (2003).  Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine. AIDS 17:2345-2349.